Applications of knot theory: chirality and the p53 protein
DOI:
https://doi.org/10.61117/ipsumtec.v6i4.271Keywords:
Knot, Chilarity, P53, DNA, Oncology drugsAbstract
In this paper we introduce some classic concepts of knot theory such as torsion, link number, mirror image, unknot number and quilarid of a knot, as well as the twist of a band. Later we translate these concepts to DNA modeling and similar molecules such as the P53 protein, which is synthesized from the DNA molecule and is known as the guardian of the genome, since it has a protocol to prevent the growth of damaged cells. Finally we established the quilarity of the P53 protein and discussed some uses in drug design.
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Copyright (c) 2023 Jonathan Toledo-Toledo, Dalia Elizabeth García Sánchez , Nancy Márquez Lázaro , Adrián López Antonio
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